Inadvertent use of the wrong cockpit control instead of the intended control is a potential situation that pilots may encounter on any aircraft type. This kind of error can occur with even the most experienced pilots and this article explores what factors can influence and lead to this type of occurrence. The resilience of the aircraft systems to cope with such an error provides effective safety barriers to prevent serious events. The aim of this article is also to raise awareness of the potential causes and effects of cockpit control confusion incidents and provide information about best practices, which can help pilots to reduce the risks that may lead to operational and safety consequences.